Course List
 Course Name  Calculations of Chemical Engineering
 Periods  1  Target Students  1  Credit(s)  3  Group  01
 Course Outline  This course ( of the 1st + 2nd semister) mainly treat with the principle of material balance and energy balance for the chemical systems. Students will learn how to deal with various systems encountered in chemical engineering industries and lab experiments, by using the basic principles of material balance and energy balance.
 Course Name  Calculus (1)
 Periods  1  Target Students  1  Credit(s)  3  Group  01
 Course Outline  1. Limites
2. Cotinueity
3. The deritive
4. Techniques of Differentiation
5. The chain rule
6. Implicite Differentiation
7. Higher-Order Derivatives
8. Applications of Differentiation
9. Logarithmic and Exponential Functions
Derivatives of Logarithmic Functions
Derivatives of Exponential Functions
10. Antiderivatives; The Indefinite Integral
Integration by Substitution; Change variables
Integration by Parts
Integrating Rational Funations; Partial Fractions



 Course Name  Chinese (1)
 Periods  1  Target Students  1  Credit(s)  2  Group  01
 Course Outline  This course is the meaning of life 'goals, covering self-life care, humanities and social care, respect for ethnic concepts, issues such as the world of macro perspective. his course is of "reading and writing, life parenting" as the goal. There are two ways to achieve this objective: 1 affective education: Teacher adjustment traditional literary intelligence pedagogy and student-centered, so freshman Chinese teaching, no longer just recite, learning and ability to instill the knowledge, but also the lives of both people emotional upbringing affection teaching, by reading and writing, and guide students' perceived self-reflection, in order to establish themselves, care for others, with a view of the world.
 Course Name  Food Chemistry
 Periods  1  Target Students  1  Credit(s)  2  Group  01
 Course Outline  (1) Carbohydrate (2) Lipids (3) proteins (4) Vitamins and minerals (5) Enzymes (6) Food additives (7) Toxic substances in food (8) Meat, plant tissue
 Course Name  Fundamental Chemistry(1)
 Periods  1  Target Students  1  Credit(s)  3  Group  01
 Course Outline  1. Atoms, Molecules and Ions 2. Stoichiometry 3. Type of Chemical Reactions and Solution Stoichiometry 4. Gases 5. Chemical Equilibrium 6. Acids and Bases 7. Applications of Aqueous Equilibria 8. Energy, Enthalpy, and Thermochemistry 9. Spontaneity, Entropy, and Free Energy 10. Electrochemistry 11. Quantum Mechanics and Atomic Theory 12. Bonding: General Concepts 13. Covalent Bonding: Orbital 14. Chemical Kinetics 15. Liquids and Solids 16. Properties of Solutions 17. The representative Elements 18. Transition Metals and Coordination Chemistry 19. The Nucleus: A Chemists View 20. Organic and Biochemical Molecules
 Course Name  Introduction To Chemical Engineering and Materials Engineering
 Periods  1  Target Students  1  Credit(s)  2  Group  01
 Course Outline  1. Introduction to Chemical Engineering 2. Introduction to Materials Engineering 3. Petrochemical Technologies 4. Electronic Industrial Technologies 5. Green Technology 6. Opto-Electronics Technologies
 Course Name  Physics(1)
 Periods  1  Target Students  1  Credit(s)  3  Group  01
 Course Outline  Introductions to the followings:
1)Vector
2)Kinetic energy
3)Thermodynamics
4)Fluid Mechanics
which will include Newton's laws, energy conservatives, classical dynamics and basic accustic theory as well as engines
 Course Name  Practical English
 Periods  1  Target Students  1  Credit(s)  2  Group  01
 Course Outline  This is an integrated course that aims to cultivate students’ reading competence, reading techniques, fluency, and comprehension. So does to enhance their vocabulary applied in various situations. Through teaching techniques, English grammar will also be strengthened.
 Course Name  Calculus (2)
 Periods  2  Target Students  1  Credit(s)  3  Group  01
 Course Outline  Chapter 5. The Indefinite Integral and Its Applications
Chapter 6. Geometry of Space
Chapter 7. Partial Derivatives
Chapter 8. Multiple Integrals



 Course Name  Chinese (2)
 Periods  2  Target Students  1  Credit(s)  2  Group  01
 Course Outline  This course is of "reading and writing, life parenting" as the goal. (A) There are two ways to achieve this objective: 1 affective education: Teacher adjustment traditional literary intelligence pedagogy and student-centered, so freshman Chinese teaching, no longer just recite, learning and ability to instill the knowledge, but also the lives of both people emotional upbringing affection teaching, by reading and writing, and guide students' perceived self-reflection, in order to establish themselves, care for others, with a view of the world. (2) both reading and writing: a powerful basis for reading ability is written in order to achieve life parenting Objectives, the course in addition to reading for the course text, another design extends extracurricular reading Read a single article and proceedings, to provide students with increased amount of reading, and strengthen reading skills. Writing is divided into classroom and extracurricular experiences writing anthology experience report must be completed each semester classroom experience writing reports and other extra-curricular experiences anthology written exercises. (Two) goals connotation: This course is the meaning of life 'goals, covering self-life care, humanities and social care, respect for ethnic concepts, issues such as the world of macro perspective; reading and writing goals connotation, is to enhance students' writing and presentation skills. This course is is divided into self-life care and the humanities and social care two large spindle unit, lower unit consists of: [Last semester] I think I am, my love our home, Love Story, life aesthetics and other four themes. [Next semester] feet to the ground line, environmental protection, cultural reflection, Reciprocity and other four themes. These eight topics as the spirit of love, with a reading book writing tool. But by the people themselves, from near and far, and gradually extended, in which themes and reflections by human respect for ethnic issues to be discussed, life aesthetics theme by the students explore the world of macro vision.
 Course Name  Fundamental Chemistry Experiment
 Periods  2  Target Students  1  Credit(s)  1  Group  01
 Course Outline  1. Separation of mixtures 2. Rate of chemical reaction 3. Determination of enthalpy 4. Solid solubility and temperature 5. Law of conservation of mass 7. Grade 3 License for chemistry
 Course Name  Fundamental Chemistry(2)
 Periods  2  Target Students  1  Credit(s)  3  Group  01
 Course Outline  1. Chemical bonding 2. Introduction to Organic Chemistry 3. Intermolecular forces and liquids and solids 4. Physical properties of solutions 5. Chemical kinetics 6. Chemical equilibrium 7. Acids and bases 8. Acid-base equilibria and solubility equilibria
 Course Name  Intermediate Practical English
 Periods  2  Target Students  1  Credit(s)  2  Group  01
 Course Outline  This is an integrated course that aims to cultivate students’ reading competence, reading techniques, fluency, and comprehension. So does to enhance their vocabulary applied in various situations. Through teaching techniques, English grammar will also be strengthened.
 Course Name  Introduction To Materials Science
 Periods  2  Target Students  1  Credit(s)  3  Group  01
 Course Outline  ch01 Introduction to Materials Science
ch02 Atomic Structure and Bonding in Solids
ch03 Metallic and Ceramic Structures
ch04 Structures of Polymers
ch05 Defects in Solids
ch06 Diffusion in Solids
ch07 Mechanical Properties of Solids
ch08 Deformation and Strengthening Mechanisms of Materials
ch09 Failure of Materials
ch10 Phase Diagrams
ch11 Phase Transformations
ch12 Electrical Properties of Materials
ch13 Types and Applications of Metals Ceramics and Polymers
ch14 Synthesis Fabrication and Processing of Metals Ceramics and Polymers
ch15 Composite Materials
ch16 Corrosion and Degradation
ch17 Thermal Properties of Materials
ch18 Magnetic Properties of Materials
ch19 Optical Properties of Materials
 Course Name  Petroleum Refining Technology
 Periods  2  Target Students  1  Credit(s)  3  Group  01
 Course Outline  1.Introduction to refining processes
2.Petroleum
3.Refining
4.Energy and petrochemicals
5.Feedstock of refinery
6.The composition and characteristics of crude oil
7.The main equipments and feedstocks of refinery
8.The products of refinery
9.The atmospheric crude distillation
10.Vacuum Distillation
 Course Name  Physics(2)
 Periods  2  Target Students  1  Credit(s)  3  Group  01
 Course Outline  1)Introductions of basic ideas of charge, electrical field, potential, current and resistance.
2) Introductions of Maxwell Equations
3) Introductions of Interference, diffaraction.
4) Introductions of general Relativity and special realtivity.
 Course Name  Composite Materials
 Periods  1  Target Students  2  Credit(s)  3  Group  01
 Course Outline  To increase students' awareness of the composites, providing conceptual thinking, creative thinking. 1 Learning composite types and development history and current situation 2 understand composite composition and characteristics of the basic 3. Understand the application of various types of composite materials and process technology 4 understand the mechanical properties of composite materials and test method .
 Course Name  Engineering Mathematics (1)
 Periods  1  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1.Matrices, Determination, Vectors. 2.Vector calculus. 3.Sysytem of Linear Differential Equations. 4.Sysytem of Nonlinear Differential Equations. 5.Fourier Series. 6.Partial Differential Equations.
 Course Name  English listening and speaking training (1)
 Periods  1  Target Students  2  Credit(s)  1  Group  01
 Course Outline  This course aims at developing the students’ listening and speaking skills in English. Students learn English conversationally by talking with each other. The text contains interesting topics for students to talk about, useful vocabulary that is presented in natural phrases and pronunciation practice to help students’ sound more fluent.
 Course Name  Introduction To Photo-electric Engineering
 Periods  1  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1. Introduction
2. Geometrical optics
3. LASER
4. Photo-electrical semiconductor
5. LED optics
 Course Name  Organic Chemistry
 Periods  1  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1.Structure and Bonding; Acids and Bases. 2.Alkanes: The Nature of Organic Compounds . 3.Alkenes and Alkynes; the Nature of Organic Reactions.4.Reactions of Alkenes and Alkynes.
5.Aromatic Compounds. Stereochemistry at Tetrahedral Centers 6.Organohalides:Nucleophilic Substitutions and Eliminations.
7.Alchols, Phenols, Ethers, and Their Sulful analgs 8.Aldehydes and Ketones: Nuclep[hilic Addition Reactions 9.Carboxylic Acids and Derivatives 10.Nucleophilic Acyl Substitution Reactions 11.Caronyl alpha-substitution reactions and condesation reactions 12.Amines 13. Structure Determination
 Course Name  Physical Chemistry(1)
 Periods  1  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1. We describe the relationship between the change in physical or chemical properties and thermodynamics.
2. We introduce the principles and applications of thermodynamics.
 Course Name  Polymer Chemistry
 Periods  1  Target Students  2  Credit(s)  3  Group  01
 Course Outline  The scope of polymer chemistry, condensation polymerizations, free-radical polymerization, reactions of synthetic polymers
 Course Name  Analytical Chemistry
 Periods  2  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1. the nature of analytical chemistry 2. the tool of analytical chemistry 3. chemical equilibrium 4. the method of classic analysis
 Course Name  Chemical Engineering Thermodynamics
 Periods  2  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1. Introduction 2. Conservation of mass and energy 3. Entropy: an additional balance equation 4. The thermodynamic properties of real substances 5. Equilibrium and stability in one-component systems 6. The Thermodynamics of multi-component mixtures 7. The estimation of the Gibbs free energy and fugacity of a component in a mixture 8. Phase equilibrium in mixtures 9. Chemical equilibrium and the balance equations for chemically reacting systems
 Course Name  Engineering Mathematics (2)
 Periods  2  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1.矩陣,行列式,與向量(Matrices, Determination, Vectors)。 2.向量微分方程(Vector calculus)。 3.線性微分方程系統(Sysytem of Linear Differential Equations)。 4.非線性微分方程系統(Sysytem of Nonlinear Differential Equations)。 5.傅立葉級數(Fourier Series)。 6.偏微分方程式(Partial Differential Equations)。
 Course Name  English Listening and Speaking Training (2)
 Periods  2  Target Students  2  Credit(s)  1  Group  01
 Course Outline  This course aims at developing the students’ listening and speaking skills in English. Students learn English conversationally by talking with each other. The text contains interesting topics for students to talk about, useful vocabulary that is presented in natural phrases and pronunciation practice to help students’ sound more fluent.
 Course Name  Instrumental Analysis
 Periods  2  Target Students  2  Credit(s)  3  Group  01
 Course Outline  Course contents incluse: Atomic spectroscopy, Molecular Spectroscopy, Separation Methods. Individual instruments will be: AA, XRD, UV-Vis, IR, NMR, MASS, SEM, GC, LC, TLC.
 Course Name  Organic Chemistry Experiments
 Periods  2  Target Students  2  Credit(s)  1  Group  01
 Course Outline  1.Useing and cleaning of important glass and instruments.
2. Basic operation of important organic experiments. For example:distillation, recrystallization,extraction
3.Synthesis and test of basic organic experiments.
 Course Name  Physical Chemistry(2)
 Periods  2  Target Students  2  Credit(s)  3  Group  01
 Course Outline  We introduce some of the principles of physical chemistry.
 Course Name  Plant Management
 Periods  2  Target Students  2  Credit(s)  3  Group  01
 Course Outline  1 Introduction to plant pipe, type of organization, factory planning and layout.
2, capacity planning, break-even.
3, material requirements planning and project management.
4, Toyota's production management.
5, process plant operations strategy, mission, characteristics and operational characteristics of the process.
 Course Name  Experiments in Instrumental Analysis
 Periods  1  Target Students  3  Credit(s)  1  Group  01
 Course Outline  Topics for the Instrumental Analysis Experiment will include: UV/Vis, AA, pH-meter, Conductivity meter, Kar-Fisher Titrator, Coloumn Chromatogrphy, UV-Fluorescence, GC, FTIR.
 Course Name  Introduction To Solar Cell Devices
 Periods  1  Target Students  3  Credit(s)  3  Group  01
 Course Outline  1.solar cell and photovoltaic conversion
2.solar photovoltaic materials and physical basis
3.solar cell preparation and structure
4.monocrystalline silicon
5.Amorphous silicon thin film
6.Polysilicon film
7.GaAs semiconductor materials
8 Dye-Sensitized Solar Cells
 Course Name  Physical Chemistry Lab.
 Periods  1  Target Students  3  Credit(s)  1  Group  01
 Course Outline  verify the principle and theory of physical chemistry.
 Course Name  Physical Education (1)
 Periods  1  Target Students  3  Credit(s)  0  Group  01
 Course Outline  Knowing the rules of basketball, volleyball, badminton, and table tennis
-learning basic skills of basketball, volleyball, badminton, and table tennis
-learning to appreciate the sports
 Course Name  Processing and Applications of Polymeric Materials
 Periods  1  Target Students  3  Credit(s)  3  Group  01
 Course Outline  1. Introduction polymeric materials
2. Introduction physical Testing of Polymer
3. Polymer Physics introduction
4. Polymer processing methods introduction (mixing, blending, Extrusion, Injection,Thermoformaing, blowing, Foaming process)
 Course Name  Thermodynamics of Materials
 Periods  1  Target Students  3  Credit(s)  3  Group  01
 Course Outline  This course will use numerous examples for the first law, second law, and others of thermodynamics issues.
 Course Name  Transport Phenomena and Unit Operation (1)
 Periods  1  Target Students  3  Credit(s)  3  Group  01
 Course Outline  Introduction
Basic principles of fluid transportation
Momentum transportation
The equipment of fluid transportation
To measurement of fluid-flow
Fluid-flow calculation
Fluid-flow through porous medium or particles bed
Filtration
Centrifugal separations
Mechanical separations
 Course Name  Core Curriculm (4) Society and Culture in Taiwan
 Periods  2  Target Students  3  Credit(s)  2  Group  01
 Course Outline  To explain and discuss Taiwan`s development of social and culture, make student identification local culture, and understanding an excuse of self scial`s transition.
 Course Name  Kinetics of Chemical Reaction Engineering
 Periods  2  Target Students  3  Credit(s)  3  Group  01
 Course Outline  1.Kinetics of Homogeneous Reactions 2.Interpretation of Batch Reactor Data 3.Introduction to Reactor Dsign 4.Ideal reactors for a Single Reaction 5.Design for Sigle Reactions 6.Design for Parallel Reactions 7.Potpourri of Multiple Reactions 8.Temperature and Pressure Effects 9.Choosing the Right Kind of Reactors
 Course Name  Physical Education (2)
 Periods  2  Target Students  3  Credit(s)  0  Group  01
 Course Outline  Knowing the rules of basketball, volleyball, badminton, and table tennis
-learning basic skills of basketball, volleyball, badminton, and table tennis
-learning to appreciate the sports
 Course Name  Polymer Nanocomposite
 Periods  2  Target Students  3  Credit(s)  3  Group  01
 Course Outline  1.Nanomaterials classification, characteristics and Nano Effect 2.Nanomaterials detection and
analysis 3.Polymer nanomaterials morphology 4. Polymer nanomaterials preparation 5. Polymer
Nanomaterials Application
 Course Name  Separation Process
 Periods  2  Target Students  3  Credit(s)  3  Group  01
 Course Outline  This course will introduce the principle of supercritical fluid technology , such as the natural product extraction, fractionation , cleaning, powder preparation, and other special applications. Enable students to understand the application of supercritical fluid production system of industrial products

 Course Name  Special Topics (1)
 Periods  2  Target Students  3  Credit(s)  1  Group  01
 Course Outline  One student is assigned to a professor, and is expected to learn how to do researches, including how to find the necessary papers, how to do the experiments, how to plot the diagrams, etc.
 Course Name  Transport Phenomena and Unit Operations (2)
 Periods  2  Target Students  3  Credit(s)  3  Group  01
 Course Outline  1. The principle and method of transportation phenomenon.
2. The principle and method of Unit operation.
 Course Name  Chemical Material Experiments
 Periods  1  Target Students  4  Credit(s)  1  Group  01
 Course Outline  Subdivided into laboratory safety and grouping, molding and sintering of ceramic, polymer mold opening and plastic, composites, material-embedded and observation, metallographic polishing and metallographic observation, material impact tests and tensile tests and crack susceptibility and temperature characteristics
 Course Name  Core Curriculm (5)-law & Civic Consciousness
 Periods  1  Target Students  4  Credit(s)  2  Group  01
 Course Outline  What is the law
Interpretation and application of the law
Legislative procedures and techniques
Constitution and basic human rights
Citizen duty
Significance of citizen participation
The separation of powers and the central government system
Local self-government and local Government
Relatives and inheritance
Environmental protection and law
Food and law
Information and law(1)Information privacy and Personal information protection Act
Information and law(2)Civil liability information activities and consumer Protection
Information and law(3)Network crime
Information and law(4)Information technology and Intellectual property rights protection
Courts and judicial system
 Course Name  Optoelectrical Polymeric Materials
 Periods  1  Target Students  4  Credit(s)  3  Group  01
 Course Outline  1. Introduction 2. Optical properties of polymers 3. Electrical properties of polymers 4.
Optoelectrical properties of Polymers 5. Preparation of OLED (organic light emitted diodes) and PLED
(polymeric LED)
 Course Name  Physical Education (3)
 Periods  1  Target Students  4  Credit(s)  0  Group  01
 Course Outline  -Knowing the rules of basketball, volleyball, badminton, and table tennis
-learning basic skills of basketball, volleyball, badminton, and table tennis
-learning to appreciate the sports
 Course Name  Process Control
 Periods  1  Target Students  4  Credit(s)  3  Group  01
 Course Outline  1. Laplace transform. 2. first order system. 3.second order system. 4. feedback control system. 5. controller and control valve. 6. stability and root locis. 7. frequence response.
 Course Name  Special Topics (2)
 Periods  1  Target Students  4  Credit(s)  1  Group  01
 Course Outline  review references, conduct experiments, analyze results, write reports and make oral presentations
 Course Name  Special Topics of Organic Chemistry
 Periods  1  Target Students  4  Credit(s)  3  Group  01
 Course Outline  Type of the organic reactions. Additions Nucleophilic substitutions and Eliminations. Aromaticity. Polyaromatics Substitution. synthsis of polyaromatic compounds. Alcohol and Phenols. Ethers and Epoxides; Thiols and Sulfides. Aldehydes and Ketones: Nucleophilic Addition Reactions. Carboxylic Acids. Carboxylic Acid derivatives and Nucleophilic Acylation Substitution reactions. Amines. Synthesis and appplications ofdiazzonium salts Carbon anions.
 Course Name  Transport Phenomena and Unit Operation (3)
 Periods  1  Target Students  4  Credit(s)  3  Group  01
 Course Outline  The student is introced to design methodology for heat and mass transfer equipment.
 Course Name  Wastewater Treatment
 Periods  1  Target Students  4  Credit(s)  3  Group  01
 Course Outline  This course lectures introduction to wastewater treatment and process analysis, wastewater characteristics, physical unit processes, chemical unit processes, biological treatments, and processing and treatment of sludge.
 Course Name  Chemical Engineering Lab.
 Periods  2  Target Students  4  Credit(s)  1  Group  01
 Course Outline  The course comprises laboratory and computer instruction. Students must complete several written assignments (lab reports). The purpose is to make students to equip with capability in “team-building”. The laboratory assignments will gradually build up to this collaborative and team-based approach. In the laboratory project, 2-3 students form a small team. Each individual analyzes their own team’s data and writes up the results on their own. For each experiment, it will need students to take three weeks for data collection, then analyze and write up a report.
 Course Name  Materials for Photo-electric Applications
 Periods  2  Target Students  4  Credit(s)  3  Group  01
 Course Outline  (1) optical materials introduction
(2) organic display materials
(3) organic field-effect transistor
(4) organic solar cells
(5) photopolymer
(6) electrochromic material
(7) organic materials for energy storage
 Course Name  Physical Education (4)
 Periods  2  Target Students  4  Credit(s)  0  Group  01
 Course Outline  -Knowing the rules of basketball, volleyball, badminton, and table tennis
-learning basic skills of basketball, volleyball, badminton, and table tennis
-learning to appreciate the sports
 Course Name  Semiconductor Materials
 Periods  2  Target Students  4  Credit(s)  3  Group  01
 Course Outline  1.Introduction of Seminconductor of process flow
2.Introduction of wafer process flow
3.Introduction of IC Package material
3.1 Introduction of Epoxy Molding Compound its
composition and appilcation
3.2 Introduction of Glue epoxy its omposition
and appilcation and appilcation
4. IC product Reliability and effect
5. IC product Failure analysis
 Course Name  Synthesis of Organic Chemistry
 Periods  2  Target Students  4  Credit(s)  3  Group  01
 Course Outline  (i) Brief Review on Organic Synthesis: In the earlier stage, human being used folk medicine such as roots, barks, grasses for treatment of illness. Since the development of organic chemistry in 1800,s year, certain drugs had been synthesized to begin the era of chemotherapy such as the discovery of sulfa drug, aspirin, ethyl ether.
(ii) Review on certain important organic reactions such as Simmon Smith reaction, Friedel Crafts reaction, Grignard reaction, Wittig reaction, Heck reaction, Suzuki reaction, Ring- Closing Metathesis,etc.
(iii) Aromatic compound synthesis: Benzocaine is used as an example to introduce the concept of retro-synthesis. Through the analytical synthesis, disconnection the structure, an ideal and practical synthetic route is established. The syntheses of some target compounds such as p-methoxyacetophenone (hawthorn blossom perfume), piperonal (perfume), antiseptic BHT (butylated hydroxytoluene), Trifluralin B (herbicides),Saccharine(sweeter) are introducedin this chapter.
(iv) The Order of Events: The order of Substituents on Aromatic Ring: The syntheses of detergent ABS (alkyl benzenesulfonate),perfume Musk ambrette,local anesthetics Propoxycaine, etc., are given to learn the order of substituents on aromatic ring.
(vi) One-Group C-X Disconnection: The concept of disconnection one bond of target compounds is introduced. The syntheses of ethers, amides, sulfides, esters, etc. are given as target compounds which include herbicide propanil, gardenia perfume, acaricide chlorbenside.
(vi) Chemoselectivity of Synthesis: When two or more unequal functional groups coexist in one molecule, the more reactive one reacts predominantly. The given examples include the synthesis of cyclomethycaine (local anesthetics), paracetamol (analgesics and antipyretics), captodiamine (antihistamine), etc.
(vii) Reversal of Polarity, Cyclization Reactions, Summary of Strategy: The alkyl group in R+-X- (alkyl halide) which is electron acceptor is converted to electron donor in Grignard reagent (R+Mg-X). In this chapter, the application of Grignard reagent, Gilman reagent (R2-Cu+Li) etc., are given. Furthermore, the application of Grubbs catalyst used for RCM (ring-closing metathesis) is introduced.
(viii) Amine synthesis: Amine drugs such as salbutamol (bronchodilator), fenfluramine (CNS stimulant), papaverine (vessel dilator), capsaicin (animal repellent, and others), propranolol (-blocker) etc., are given as examples for retro-synthesis.
(ix) Protecting Groups and Its Application on Synthesis: The protecting groups for alcohols, amines, carbonyl compounds, carboxylic acids and etc., and their application in syntheses are given.
(x) Alcohol synthesis: In this chapter, the strategies for alcohol syntheses including diphenidol (anti-motion sickness), pirindol (kolax) (muscle relaxant) are given.
(xi) Stereoselectivity and Regioselectivity on Organic Synthesis: The syntheses of chiral compounds such as thalidomide, fluoxetine etc., will be given as examples, and 1,2- or 1,4-addition of - unsaturated carbonyl compounds will be given as examples of regioselectivity.
(xii) Alkenes synthesis: Dehydration of alcohols and the Wittig reaction are introduced for the synthesis of alkenes. Palanil (dye), tamoxifen(anti-cancer drug), dispalure (insect pheromone) are given as examples.
(xii) The Application of Carbonyl Group on Organic Synthesis: The application of malonic ester synthesis, acetoacetic ester synthesis, Robinson annulation, Claisen condensation, and Cannizzaro reaction, etc., on organic synthesis is given as examples.
(xiii) Use of Aliphatic Nitro Compounds in Synthesis: Nitro Group (-NO2) which can be reduced to amines (-NH2), and can be oxidized to carbonyl group (C=O), is widely used in organic synthesis such as chlorphentermine (anti-appetite), diamines (monomer for polyamide), etc.